Kumail Nanjiani will be a familiar face to fans of HBO’s “Silicon Valley,” or “Portlandia,” or appearances on dozens of other sitcoms and sketch shows, but the very funny and surprisingly moving THE BIG SICK should make him a familiar face to many more. The film - co-written with Nanjiani’s wife Emily V. Gordon - tells the story of their unusual courtship, which featured not only family tensions due to cultural differences (Nanjiani is Pakistani-American, Gordon is white) but, more significantly, a life-threatening illness that struck Gordon while the two were still just dating.

Nanjiani talks about the art of co-writing a screenplay with your spouse (spoiler: it helps to have Judd Apatow mentor you), the most difficult scene he’s ever had to shoot, and he shares his Top 5 Most Influential Movies. Plus, he and Adam chat about their college days - that they nearly spent together.